新加坡鄧懿禎、
報告題目：The Role of Autophagy in Fungal Development and Pathogenesis
報告人：鄧懿禎 博士
報告題目：Post-transcriptional Autoregulation of mHuR Expression
報告人：
報告時間：
報告地點：六號樓學術報告廳
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人事處
生命科學學院
鄧懿禎 博士 簡介
Contact
Deng Yizhen 鄧懿禎
Address: (Home)
(Working) Fungal Patho-biology Group, Temasek Life sciences Laboratory, 1 Research Link, National University of Singapore 117604
E-mail: yizhen@tll.org.sg
Education
1999-2003 B. Sc, School of Lifesciences,
2005-2011 Ph. D,
Working experiences
2004.9-2011.2 Temasek Lifesciences Laboratory, Junior Research Fellow
2011.2-now (current contract ends by Feb 2013) Temasek Lifesciences Laboratory Research Fellow (post-doctoral)
Awards
2007.8-2010.8 Singapore Millenium Foundation Scholarship for Ph.D student
International conferences attending
2007.10 The 4th IRBC (International Rice Blast Conference),
2008.6 Gordon research conference on The Cellular and Molecular Fungal Biology
2009.8 EMBO meeting,
2009.11 International meeting on Peroxisome research,
2010.4 Gordon research conference on Autophagy in Stress, Development and Disease,
Publication
Deng YZ, Qu ZW, He YL, Naqvi NI. (2012) Sorting Nexin Snx41 is essential for conidiation and mediates glutathione-based antioxidant defense during invasive growth in Magnaporthe oryzae. Autophagy 8(7) (In press)
Deng, YZ and NI Naqvi. 2010. A vacuolar glucoamylase, Sga1, participates in glycogen autophagy for proper asexual differentiation in Magnaporthe oryzae. Autophagy 6: 455-461.
Deng, YZ, M Ramos-Pamplona and NI Naqvi. 2009. Autophagy-assisted glycogen catabolism regulates asexual differentiation in Magnaporthe oryzae. Autophagy 5: 33-43. Cover feature.
Deng, YZ, M Ramos-Pamplona and NI Naqvi. 2008. Methods for the functional analysis of macroautophagy in filamentous fungi. Methods in Enzymology. 451: 295-310.
Sun, CB, A Suresh, YZ Deng and NI Naqvi. 2006. A Multidrug Resistance Transporter in Magnaporthe is Required for Host Penetration and for Survival during Oxidative Stress. The Plant Cell. 18: 3686-3705.
Manuscript in preparation:
Deng, YZ and
Deng, YZ and
Referee
Prof. Naweed NAQVI
Tel: (65) 6872 7000, 6872 7493 (DID) or 6872 7087 (lab)
Email: naweed@tll.org.sg
Prof. Snezhaka OLIFERENKO
Tel: (65) 6872 7000, 6872 7490 (DID) or 6872 7494 (lab)
Email: snejana@tll.org.sg
Contact
Dai Weijun 戴偉君
Address: Division of Molecular & Cell Biology,School of Biological Sciences,
Tel. 65-81966859 (mobile)
Email: daiweijun@gmail.com
wjdai@ntu.edu.sg
Education
1997-2001 B. Sc, Sun-Yat sen (ZhongShan) University,
2001
2005-2008 Ph.D., Sun-Yat sen (ZhongShan) University,
2008 July-present Postdoctoral Fellow
Research interests (stem cell / neuron differentiation /microRNA/cancer)
My research interest lies in understanding the significance of post-transcriptional RNA-based processes for stem cell differentiation (particularly in neuron differentiation), microRNA regulation and cancer development. Gene expression in eukaryotes is subject to extensive regulation at posttranscriptional levels. One of the most important sites of control involves mRNA 3′ untranslated regions (
Ph.D. research topic
Establishment of symbiosis between certain host plants and nitrogen-fixing bacteria depends on type 3 secretion system (T3SS) effectors. NopT is a novel T3SS effector of Rhizobium sp. strain NGR234. NopT possesses autoproteolytic activity. This functional protease activity leads to symbiosis-promoting on Phaseolus vulgaris cv. Yudou No. 1; Tephrosia vogelii while deleterious effects upon Crotalaria juncea.
PUBLICATIONS
Dai WJ, Zhang G, Makeyev EV. RNA-binding protein HuR autoregulates its expression by promoting alternative polyadenylation site usage. Nucleic Acids Res. 2011 Sep 24. Featured Articles
Dai WJ, Zeng Y, Xie ZP, Staehelin C. Symbiosis-promoting and deleterious effects of NopT, a novel type 3 effector of Rhizobium sp. strain NGR234.J Bacteriol. 2008 Jul;190(14):5101-10. Epub 2008 May 16.
Yang FJ, Cheng LL, Zhang L, Dai WJ, Liu Z, Yao N, Xie ZP, Staehelin C. Y4lO of Rhizobium sp. strain NGR234 is a symbiotic determinant required for symbiosome differentiation.J Bacteriol. 2009 Feb;191(3):735-46. Epub 2008 Dec 5.
Referee
Prof. Eugene Makeyev
Nanyang Technological University
Phone (work): +65-6513 8151
Email: makeyev@ntu.edu.sg
Prof. Christian Staehelin
State Key Laboratory of Biocontrol
Sun Yat-sen (Zhongshan) University, East Campus
Email: cst@mail.sysu.edu.cn
